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Description Pentobarbital is in a group of drugs called barbiturates (bar-BIT-chur-ates). Pentobarbital slows the activity of your brain and nervous system.Pentobarbital is used short-term to treat insomnia. Pentobarbital is also used as an emergency treatment for seizures, and to cause you to fall asleep for surgery.Pentobarbital may also be used for other purposes not listed in this medication guide.Visit our website http://wadoresearchchem.com/